STRATEGY OF INFUSION-TRANSFUSION THERAPY IN OPERATIONS WITH MASSIVE BLOODWORK IN CHILDREN WITH TUMOR ABOMALOMAL LOCALIZATION TUMORS

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Abstract

Surgeries for thoracoabdominal tumors in children predispose to water and electrolyte imbalance, imbalance in the coagulation system, etc. In spite of abundance of recommendations for children, the volume of basic infusion therapy is uncertain.

Study purpose. To estimate the clinical effectiveness of the conducted infusion therapy with isotonic balanced electrolyte solution in children who underwent thoracoabdominal surgeries accompanied with massive blood loss and a complex estimation of the conducted infusion and transfusion therapy.

Materials and methods. The intraoperative and early postoperative (days 1–5) periods were analyzed in 22 patients (ASA II–III) who underwent an operation for thoracoabdominal malignant tumors with massive perioperative blood loss in 2016–2017. Group I included 11 patients who had infusion with balanced crystalloid solutions of 5 to 10 ml/kg/hour under combined anesthesia. Group II includes 11 patients who had infusion with balanced crystalloid solutions of 11 to 20 ml/kg/hour under combined anesthesia.

Results. According to the conducted study, a higher hemodynamic stability was observed in patients from the group of basic infusion therapy with balanced crystalloid solutions of 11–20 ml/kg/hour. It was expressed as the decrease of the mean dose of the used vasopressors and volume of the infusion of colloidal solutions. The patients also had a less intense response to stress.

About the authors

E. I. Belousova

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute

Email: fake@neicon.ru

Ekaterina I. Belousova – Anesthesiologist, PhD, Anesthesiology and intensive care department

Kashirskoye Shosse, 24, 115478, Moscow

Russian Federation

N. V. Matinyan

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute;
Pediatric anesthesiology and intensive care department, Pirogov Russian National Research Medical University

Author for correspondence.
Email: n9031990633@yandex.ru

Nune V. Matinyan – MD, PhD, professor, Head of Anesthesiology and intensive care department, Pediatric Oncology and Hematology Research Institute, Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia

Kashirskoye Shosse, 24, 115478, Moscow, Ostrovitianov str. 1, 117997, Moscow


Russian Federation

L. А. Martynov

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute

Email: fake@neicon.ru

Leonid A. Martynov – Anesthesiologist, Anesthesiology and intensive care department

Kashirskoye Shosse, 24, 115478, Moscow

Russian Federation

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Copyright (c) 2018 Belousova E.I., Matinyan N.V., Martynov L.А.

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