RESULTS OF SURGICAL TREATMENT OF NEWBORNS WITH OMPHALOCELE

Yu. A. Kozlov; Козлов Ю. А.; V. A. Novozhilov; Новожилов В. А.; A. A. Rasputin; Распутин А. А.; P. I. Baradieva; Барадиева П. Ж.; D. A. Zvonkov; Звонков Д. А.; A. D. Timofeev; Тимофеев А. Д.; N. V. Rasputina; Распутина Н. В.; N. N. Kuznetsova; Кузнецова Н. Н.

doi:10.17816/psaic368

RESULTS OF SURGICAL TREATMENT OF NEWBORNS WITH OMPHALOCELE

Authors: Kozlov Y.A.¹^,2^,3, Novozhilov V.A.¹^,2^,3, Rasputin A.A.¹, Baradieva P.I.¹, Zvonkov D.A.³, Timofeev A.D.³, Rasputina N.V.¹, Kuznetsova N.N.¹
Affiliations:
1. Municipal Ivan-Matryona Children’s Clinical Hospital, Irkutsk
2. Irkutsk State Medical Post-Graduation Academy
3. Irkutsk State Medical University
Issue: Vol 7, No 4 (2017)
Pages: 18-25
Section: Original Study Articles
URL: https://rps-journal.ru/jour/article/view/368
DOI: https://doi.org/10.17816/psaic368
ID: 368

Cite item

Full Text

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

The surgical treatment results for 27 patients with omphalocele taken to the Ivan-Matryona Children’sClinicalHospitalinIrkutskfrom 2002 to 2017 were submitted. The study methodology consists in the comparative analysis of effectiveness of different surgical technologies including one-step (17 patients) and stage (10 patients) abdominal wall defect repair. ALV duration, time of transition to complete parenteral nutrition, hospital stay duration, gastroesophageal reflux occurrence, ventral hernia and lethality are used as comparison criteria. There are no significant differences between the groups of patients randomized by gestational age, afterbirth age and body weight. Significant disturbances by extubation period were stated (1.76 vs 5.4 days, p=0.0001).

A significant decreased transition time to complete enteral nutrition (20.53 vs 27.60 days, p=0.020) was observed in the group of one-stage defect closure. Fundoplication frequency was higher in those patients who underwent multistage surgeries (11.76% vs 30%, p=0.326). Ventral hernia formation frequency was also higher in the group of stage closure (8.57% vs 30%, p=0.128). Study results reveal the advantage of one-stage abdominal repair in surgical treatment of newborns with omphalocele.

Keywords

omphalocele, primary repair, stage treatment

References

Islam S. Congenital abdominal wall defects. In: Holcomb G., Murphy J., Ostlie D., editor. Aschcrafts pediatric surgery, sixth edition. London, New York: Elsevier Saunders; 2014. p.660–672.
Козлов Ю. А., Новожилов В. А., Ковальков К. А. и др. Врожденные дефекты брюшной стенки. Хирургия. Журнал им. Н. И. Пирогова 2016;5:74–81.
Kozlov Y., Novozhilov V., Kovalkov K. et al. Congenital abdominal wall defects. Khirurgiya im N. I. Pirogova 2016;5:74–81. (in Russian)
Feldkamp M., Carey J., Sadler T. Development of gastroshisis: review of hypotheses, a novel hypothesis, and implications for research. Am J Med Genet A 2007;43:639–652.
Maksoud-Filho J., Tannuri U., da Silva M. et al. The outcome of newborns with abdominal wall defects according to the method of abdominal closure: the experience of a single center. Pediatr Surg Int 2006;22:503–7.
Van Eijck F., Aronson D., Hoogeveen Y. et al. Past and current surgical treatment of giant omphalocele: outcome of a questionnaire sent to authors. J Pediatr Surg 2011;46:482–6.
Shermeta D. W., Haller J. A. Jr. A new preformed transparent silo for the management of gastroschisis. J Pediatr Surg. 1975; 10 (6):973–975.
Almond S., Reyna R., Barganski N. et al. Nonoperative management of a giant omphalocele using a silver impregnated hydrofiber dressing: a case report. J Pediatr Surg 2010;45:1546–9.
Brantberg A., Blaas H., Haugen S. et al. Characteristics and outcome of 90 cases of fetal omphalocele. Ultrasound Obstet Gynecol 2005;26:527–37.
Cohen-Overbeek T., Tong W., Hatzmann T. et al. Omphalocele: comparison of outcome following prenatal or postnatal diagnosis. Ultrasound Obstet Gynecol 2010;36:687–92.
Frolov P., Alali J., Klein M. Clinical risk factors for gastroschisis and omphalocele in humans: a review of the literature. Pediatr Surg Int 2010;26:1135–48.
Amoury R., Ashcraft K., Holder T. Gastroschisis complicated by intestinal atresia. Surgery 1977;82:373–81.
Nocholas S., Stamilio D., Dicke J. et al. Predicting adverse neonatal outcomes in fetuses with abdominal wall defects using prenatal risk factors. Am J Obstet Gynecol 2009;201:383.
Kamata S., Usui N., Sawai T. et al. Prenatal detection of pulmonary hypoplasia in giant omphalocele. Pediatr Surg Int 2008;24:107–11.
Hidaka N., Murata M., Yumoto Y. et al. Characteristics and perinatal course of prenatally diagnosed fetal abdominal wall defects managed in a tertiary center in Japan. J Obstet Gynaecol Res 2009;35:40–7.
Montero F., Simpson L., Brady P. et al. Fetal omphalocele ratios predict outcomes in prenatally diagnosed omphalocele. Am J Obstet Gynecol 2011;205:284.
Kleinrouweler C., Kuijper C., van Zalen-Sprock M. et al. Characteristics and outcome and the omphalocele circumference / abdominal circumference ratio in prenatally diagnosed fetal omphalocele. Fetal Diagn Ther 2011;30‑60‑9.
Mortellaro V., St Peter S., Fike F. et al. Review of the evidence on the closure of abdominal wall defects. Pediatr Surg Int 2011;27:391–7.
Islam S. Clinical care outcomes in abdominal wall defects. Curr Opin Pediatr 2008;20:305–10.
Rijhwani A., Davenport M., Dawrant M. et al. Definitive surgical management of antenatally diagnosed exomphalos. J Pediatr Surg 2004;40:516–22.
Delorimier A., Adzick S., Harrison M. et al. Amnion inversion in the treatment of giant omphalocele. J Pediatr Surg 1991;26:804–7.
Yokomori K., Ohkura M., Kitano Y. et al. Advantages and pitfalls of amnion inversion repair for the treatment of large unruptured omphalocele: results of 22 cases. J Pediatr Surg 1992;27:882–4.
Alaish S., Strauch E. The use of Alloderm in the closure of a giant omphalocele. J Pediatr Surg 2006;41: e37–9.
Baird R., Gholoum S., Laberge J. et al. Management of a giant omphalocele with an external skin closure system. J Pediatr Surg 2010;45: E17–20.
Kilbride K., Cooney D., Custer M. Vacuum-assisted closure: a new method for treating patients with giant omphalocele. J Pediatr Surg 2006;41:212–15.
Gross R. A new method for surgical treatment of a large omphalocele. Surgery 1948;24:277–92.
Brown A., Roty A., Kilway J. Increased survival with new techniques in treatment of gastroschisis. Am Surg 1978;44:417–20.
Dariel A., Poocharoen W., de Silva N. et al. Secondary plastic closure of gastroschisis is associated with a lower incidence of mechanical ventilation. Eur J Pediatr Surg. 2015;25:34–40.
Biard J., Wilson R., Johnson M. et al. Prenatally diagnosed giant omphalocele: short- and long-term outcomes. Prenat Diagn 2004;24:434–9.
Van Eijck F., de Blaauw I., Bleichrodt R. et al. Closure a giant omphalocele by the abdominal wall component separation technique in infants. J Pediatr Surg 2008;43:246–50.
De Ugarte D., Asch M., Hedrick M. et al. The use of tissue expanders in the closure of a giant omphalocele. J Pediatr Surg 2004;39:613–15.

Supplementary files

Supplementary Files

Action

1. JATS XML

Download

Username
Password
Remember me

Forgot password?	Register

Username
Password
Remember me

Forgot password?	Register

RESULTS OF SURGICAL TREATMENT OF NEWBORNS WITH OMPHALOCELE

Full Text

Abstract

Keywords

About the authors

References

Supplementary files

This website uses cookies